• Jeffrey Townsend

Essential Ingredients to Consider When Formulating Weight-Loss Products

In the sports nutrition market, your fat-burner can make or break your brand. Weight-loss supplements are designed to help boost metabolism, maximize your training and torch body fat. Knowing that diet is 80% of the battle, an effective thermogenic is meant to be fuel on the fire when it comes to your weight loss goals. But what makes an effective fat burning supplement? Today on the Accelerated Genetix Blog, we discuss essential ingredients to consider when formulating weight-loss products.


Caffeine is a good staple ingredient for any weight-loss product. Caffeine is a stimulant found abundantly in coca, coffee beans, tea leaves and other natural foods and plants. This powerful alkaline helps elevate the metabolic rate, helping the body efficiently burn more calories. Caffeine helps augment both aerobic and anaerobic exercises, giving athletes a substantial increase in athletic performance. Caffeine has also shown to help lower the rate of exertion, giving users the ability to workout harder for longer periods of time.


L-Carnitine is an amino acid that is naturally produced in the body in the liver and kidneys from the amino acids Lysine and Methionine and is stored mostly in muscle. L-Carnitine comes in two forms: D-Carnitine and L-Carnitine. Acetyl L-Carnitine is another effective form of L-Carnitine that has shown to produce energy and acts as a powerful antioxidant. L-Carnitine helps transport fat into the mitochondria of cells, there it’s oxidized and used as fuel (or converted to ATP).


Yohimbine is another powerful stimulant that should be considered when formulating your weight-loss aid. Yohimbine comes from the bark of a west African evergreen tree and helps to dilate the blood vessels to help lower blood pressure. This powerful dietary supplement works by blocking receptors in the body known as alpha-2 adrenergic receptors located in fat cells. Yohimbine increases adrenaline levels in the body, as well as inhibits a regulatory process in fat cells.

Green Tea Extract

Green Tea Extract has become a common ingredient in weight-loss products due to its antioxidant powers and its ability to raise caloric expenditure. Due to its antioxidant epigallocatechin gallate, green tea enhances the activity of neurotransmitters like dopamine and epinephrine, which drastically effects the body’s fat burning capabilities.


Another effective stimulant to consider is Synephrine which comes from Citrus aurantium tree leaves. Synephrine stimulates beta-adrenergic receptors, which helps increase concentrations of catecholamines in the blood. This process activates lipolysis in adipocytes which is used to mobilize stored energy during exercise. Synephrine is known for its ability to decrease appetite and increase metabolism without effecting blood pressure or heart rate.

Pyrroloquinoline Quinone (PQQ)

PQQ is another organic compound found in fermented soybeans. PQQ has become an effective fat burning agent due to its ability to create new mitochondria in cells which increases metabolic rate. This powerful compound helps increase the body’s natural production of Irisin, a hormone that’s considered one of the best benefits your body produces from physical activity.


Capsaicin comes from capsacinoids, the compounds found in peppers that give them spice or heat. Capsaicin helps increase metabolic expenditure due to beta-adrenergic stimulation. This increase in energy expenditure and concomitant decrease in respiratory quotient positively affects fat oxidation. Research has shown eating capsaicin-rich foods can help speed up metabolism, help burn fat and suppress appetite.


Forskolin is another organic compound classified as a terpene and comes from the Indian plant Coleus Forskohlii. This fat-burning compound helps increase intracellular cAMP levels by elevating the adenyl cyclase enzyme. Forskolin has also shown to elevate lipolysis in cells and increase testosterone levels.

When formulating a weight-loss product there are a ton of ingredients to consider. As health and fitness continue to be more important to consumers everyday life, it’s essential that your supplement company formulate a well-rounded fat burning product. At Accelerated Genetix you can choose from several house formula’s or we can assist in a custom formulation. Reach out to info@agenetix.com to speak with an AG account manager and launch your weight-loss product today!

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